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LOS ANGELES — Gene Wilder, the frizzy-haired actor who brought his deft comedic touch to such unforgettable roles as the neurotic accountant in “The Producers” and the mad scientist of “Young Frankenstein,” has died. He was 83.

Wilder’s nephew said Monday that the actor and writer died late Sunday at his home in Stamford, Connecticut, from complications from Alzheimer’s disease.

Jordan Walker-Pearlman said in a statement that Wilder was diagnosed with the disease three years ago, but kept the condition private so as not to disappoint fans.

“He simply couldn’t bear the idea of one less smile in the world,” Walker-Pearlman said.

Wilder started his acting career on the stage, but millions knew him from his work in the movies, especially his collaborations with Mel Brooks on “The Producers,” ”Blazing Saddles” and “Young Frankenstein.” The last film — with Wilder playing a California-born descendant of the mad scientist, insisting that his name is pronounced “Frahn-ken-SHTEEN” — was co-written by Brooks and Wilder.

  • Actor Gene Wilder is shown in December 1980. (AP Photo)

    The Associated Press

    Actor Gene Wilder is shown in December 1980.

  • American comic actor Gene Wilder, originally Jerry Silkman stars with nightclub comedian Richard Pryor in the action comedy 'Silver Streak'. Directed by Arthur Hiller, the film was chosen for the 31st Royal Film Festival. (Photo by Hulton Archive/Getty Images)

    Hulton Archive, Getty Images

    American comic actor Gene Wilder, originally Jerry Silkman stars with nightclub comedian Richard Pryor in the action comedy 'Silver Streak'. Directed by Arthur Hiller, the film was chosen for the 31st Royal Film Festival.

  • Gilda Radner, left, and Gene Wilder are shown in a scene from the film "Hanky Panky," directed by Sidney Poitier, Aug. 27, 1981. (AP Photo/Bill Polo)

    Bill Polo, The Associated Press

    Gilda Radner, left, and Gene Wilder are shown in a scene from the film "Hanky Panky," directed by Sidney Poitier, Aug. 27, 1981.

  • Comedian Gilda Radner, left, and Gene Wilder, kiss for photographers in this photograph following their private wedding ceremony, 1984, France. (AP Photo)

    The Associated Press

    Comedian Gilda Radner, left, and Gene Wilder, kiss for photographers in this photograph following their private wedding ceremony, 1984, France.

  • Actor/director Sidney Poitier, left, gestures on Wednesday, August 26, 1981 in Boston while speaking with Gene Wilder and Gilda Radner, two of the stars of “Traces,” a comedy currently being filmed in several locations in Boston. This scene is taking place at the Commonwealth Pier. Poitier has put aside his acting talents to direct “Traces,” which also stars Richard Widmark. (AP Photo/Bill Polo)

    Bill Polo, The Associated Press

    Actor/director Sidney Poitier, left, gestures on Wednesday, August 26, 1981 in Boston while speaking with Gene Wilder and Gilda Radner, two of the stars of “Traces,” a comedy currently being filmed in several locations in Boston. This scene is taking place at the Commonwealth Pier. Poitier has put aside his acting talents to direct “Traces,” which also stars Richard Widmark.

  • Actor Gene Wilder is shown at NBC studios, June 26, 1979, New York. Wilder had just appeared on the “Today” show to promote his Warner’s Bros. film, “The Frisco Kid.” (AP Photo/Dave Pickoff)

    Dave Pickoff, The Associated Press

    Actor Gene Wilder is shown at NBC studios, June 26, 1979, New York. Wilder had just appeared on the “Today” show to promote his Warner’s Bros. film, “The Frisco Kid.”

  • FILE - In this April 9, 2008 file photo, actor Gene Wilder listens as he is introduced to receive the Governor's Awards for Excellence in Culture and Tourism at the Legislative Office Building in Hartford, Conn. Wilder, who starred in such film classics as "Willy Wonka and the Chocolate Factory" and "Young Frankenstein" has died. He was 83. (AP Photo/Jessica Hill, File)

    Jessica Hill, The Associated Press

    FILE - In this April 9, 2008 file photo, actor Gene Wilder listens as he is introduced to receive the Governor's Awards for Excellence in Culture and Tourism at the Legislative Office Building in Hartford, Conn. Wilder, who starred in such film classics as "Willy Wonka and the Chocolate Factory" and "Young Frankenstein" has died. He was 83.

  • Gene Wilder and his wife Karen Boyer watch as Shahar Peer of Israel takes on Anna Chakvetadze of Russia during day ten of the 2007 U.S. Open at the Billie Jean King National Tennis Center on September 5, 2007 in the Flushing neighborhood of the Queens borough of New York City. (Photo by Al Bello/Getty Images)

    Al Bello, Getty Images

    Gene Wilder and his wife Karen Boyer watch as Shahar Peer of Israel takes on Anna Chakvetadze of Russia during day ten of the 2007 U.S. Open at the Billie Jean King National Tennis Center on September 5, 2007 in the Flushing neighborhood of the Queens borough of New York City.

  • Actor Gene Wilder poses as he signs copies of his autobiography "Kiss Me Like A Stranger", at Waterstone's, Oxford Street on June 7, 2005 in London, England. The memoirs give an insight into Wilder's failed love life, his experiences of working with stars such as Richard Pryor and Woody Allen, his fight with, and victory over, cancer, and his time in the UK studying acting at the Bristol Old Vic. (Photo by MJ Kim/Getty Images)

    MJ Kim, Getty Images

    Actor Gene Wilder poses as he signs copies of his autobiography "Kiss Me Like A Stranger", at Waterstone's, Oxford Street on June 7, 2005 in London, England. The memoirs give an insight into Wilder's failed love life, his experiences of working with stars such as Richard Pryor and Woody Allen, his fight with, and victory over, cancer, and his time in the UK studying acting at the Bristol Old Vic.

  • In this March 16, 2005 file photo, actor Gene Wilder speaks about his life and career at Boston University in Boston. Wilder, who starred in such film classics as "Willy Wonka and the Chocolate Factory" and "Young Frankenstein" has died. He was 83. (AP Photo/Steven Senne, File)

    Steven Senne, The Associated Press

    In this March 16, 2005 file photo, actor Gene Wilder speaks about his life and career at Boston University in Boston. Wilder, who starred in such film classics as "Willy Wonka and the Chocolate Factory" and "Young Frankenstein" has died. He was 83.

  • Lee Meredith, upper right, and Kenneth Mars, upper left with Gene Wilder and Zero Mostel in a scene from the movie "The Producers" July 1967. (AP Photo)

    The Associated Press

    Lee Meredith, upper right, and Kenneth Mars, upper left with Gene Wilder and Zero Mostel in a scene from the movie "The Producers" July 1967.

  • Gene Wilder is shown in character as he films Tri Star Pictures "See No Evil, Hear No Evil" with Richard Pryor in 1989. (AP Photo)

    The Associated Press

    Gene Wilder is shown in character as he films Tri Star Pictures "See No Evil, Hear No Evil" with Richard Pryor in 1989.

  • Actor and author Gene Wilder autographs copies of his new book 'The Woman Who Wouldn't' at Barnes & Noble Bookstore at The Grove on March 17, 2008 in West Hollywood, California. (Photo by Charley Gallay/Getty Images)

    Charley Gallay, Getty Images

    Actor and author Gene Wilder autographs copies of his new book 'The Woman Who Wouldn't' at Barnes & Noble Bookstore at The Grove on March 17, 2008 in West Hollywood, California. (Photo by Charley Gallay/Getty Images)

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“Gene Wilder, one of the truly great talents of our time, is gone,” Brooks wrote in a statement Monday. “He blessed every film we did together with his special magic and he blessed my life with his friendship. He will be so missed.”

With his unkempt hair and big, buggy eyes, Wilder was a master at playing panicked characters caught up in schemes that only a madman such as Brooks could devise, whether reviving a monster in “Young Frankenstein” or bilking Broadway in “The Producers.” Brooks would call him “God’s perfect prey, the victim in all of us.”

But he also knew how to keep it cool as the boozing gunslinger in “Blazing Saddles” or the charming candy man in the children’s favorite “Willy Wonka and the Chocolate Factory.” His craziest role: the therapist having an affair with a sheep in Woody Allen’s “Everything You Wanted to Know About Sex.”

“The greatest comedic mind of my childhood is now gone,” actor Josh Gad wrote on Twitter. “#RIP #GeneWilder & thank you 4 your pure imagination. This one hits hard.”

Tweeted Jim Carrey: “Gene Wilder was one of the funniest and sweetest energies ever to take a human form. If there’s a heaven he has a Golden Ticket.”

Wilder was close friends with Richard Pryor and their contrasting personas — Wilder uptight, Pryor loose — were ideal for comedy. They co-starred in four films: “Silver Streak,” ”Stir Crazy,” ”See No Evil, Hear No Evil” and “Another You.” And they created several memorable scenes, particularly when Pryor provided Wilder with directions on how to “act black” as they tried to avoid police in “Silver Streak.”

But Wilder would insist in a 2013 interview that he was no comedian. He told interviewer Robert Osborne it was the biggest misconception about him.

“What a comic, what a funny guy, all that stuff! And I’m not. I’m really not. Except in a comedy in films,” Wilder said. “But I make my wife laugh once or twice in the house, but nothing special. But when people see me in a movie and it’s funny then they stop and say things to me about ‘how funny you were.’ But I don’t think I’m that funny. I think I can be in the movies.”

In 1968, Wilder received an Oscar nomination for his work in Brooks’ “The Producers.” He played the introverted Leo Bloom, an accountant who discovers the liberating joys of greed and corruption as he and Max Bialystock (Zero Mostel) conceive a Broadway flop titled “Springtime For Hitler” and plan to flee with the money raised for the show’s production. Matthew Broderick played Wilder’s role in the 2001 Broadway stage revival of the show.

Though they collaborated on film, Wilder and Brooks met through the theater. Wilder was in a play with Brooks’ then-future wife, Anne Bancroft, who introduced the pair backstage in 1963.

Wilder, a Milwaukee native, was born Jerome Silberman on June 11, 1933. His father was a Russian emigre, his mother was of Polish descent. When he was 6, Wilder’s mother suffered a heart attack that left her a semi-invalid. He soon began improvising comedy skits to entertain her, the first indication of his future career.

American comic actor Gene Wilder, originally Jerry Silberman stars with nightclub comedian Richard Pryor in the action comedy 'Silver Streak'. Directed by Arthur Hiller, the film was chosen for the 31st Royal Film Festival. (Photo by Hulton Archive/Getty Images)
Hulton Archive, Getty Images
American comic actor Gene Wilder, originally Jerry Silberman stars with nightclub comedian Richard Pryor in the action comedy ‘Silver Streak’. Directed by Arthur Hiller, the film was chosen for the 31st Royal Film Festival.

He started taking acting classes at age 12 and continued performing and taking lesson through college. In 1961, Wilder became a member of Lee Strasberg’s prestigious Actor’s Studio in Manhattan.

That same year, he made both his off-Broadway and Broadway debuts. He won the Clarence Derwent Award, given to promising newcomers, for the Broadway work in Graham Greene’s comedy “The Complaisant Lover.”

He used his new name, Gene Wilder, for the off-Broadway and Broadway roles. He lifted the first name from the character Eugene Gant in Thomas Wolfe’s “Look Back, Homeward Angel,” while the last name was clipped from playwright Thornton Wilder. A key break came when he co-starred with Bancroft in Bertolt Brecht’s “Mother Courage,” and met Brooks, her future husband.

“I was having trouble with one little section of the play, and he gave me tips on how to act. He said, ‘That’s a song and dance. He’s proselytizing about communism. Just skip over it, sing and dance over it, and get on to the good stuff.’ And he was right,” Wilder later explained.

Before starring in “The Producers,” he had a small role as the hostage of gangsters in the 1967 classic “Bonnie and Clyde.” He peaked in the mid-1970s with the twin Brooks hits “Blazing Saddles” and “Young Frankenstein.”

He went on to write several screenplays and direct several films. In 1982, while making the generally forgettable “Hanky-Panky,” he fell in love with co-star Gilda Radner. They were married in 1984, and co-starred in two Wilder-penned films: “The Woman in Red” and “Haunted Honeymoon.”

After Radner died of ovarian cancer in 1989, Wilder spent much of his time after promoting cancer research and opened a support facility for cancer patients. In 1991, he testified before Congress about the need for increased testing for cancer.

That same year, he appeared in his final film role: “Another You” with Pryor.

Wilder worked mostly in television in recent years, including appearances on “Will & Grace” — including one that earned him an Emmy Award for outstanding guest actor — and a starring role in the short-lived sitcom “Something Wilder.” In 2015, he was among the voices in the animated “The Yo Gabba Gabba! Movie 2.”

As for why he stopped appearing on the big screen, Wilder said in 2013 he was turned off by the noise and foul language in modern movies.

“I didn’t want to do the kind of junk I was seeing,” he said in an interview. “I didn’t want to do 3D for instance. I didn’t want to do ones where there’s just bombing and loud and swearing, so much swearing… can’t they just stop and talk instead of swearing?”

Wilder is survived by his wife, Karen, whom he married in 1991, and his daughter from a previous marriage, Katherine, from whom he was estranged.